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5 Symptoms of Opioid Withdrawal

Man dealing with the symptoms of opioid withdrawal

The symptoms of opioid withdrawal are not pleasant, and they often require professional treatment to help manage them safely. There is no shame in seeking treatment for opioid addiction, as it is a complex and chronic disease that can be difficult to overcome on your own.

If you or a loved one want more information about the signs of opioid withdrawal or are interested in treatment, contact Vertava Health today at 844.470.0410. Our opioid rehab center can help.

What Are Opioids?

Opioids are developed derivatives of opium, which originate from the poppy plant. Opioids are a broad class of drugs typically prescribed to manage moderate to extreme pain symptoms. The term narcotic is used to discuss both opioids and opiates. Examples of opioid drugs include:

  • Oxycontin (Oxycodone)
  • Vicodin (hydrocodone and acetaminophen)
  • Dilaudid (hydromorphone)
  • Morphine
  • Fentanyl
  • Heroin

What Causes Opioid Withdrawal?

Over time, your body becomes less sensitive to the effects of opioids. This tolerance causes the body to need larger doses of the drug to achieve the same effect, and it can increase the risk of overdose and death. After a while, your brain thinks it is functioning normally while on the drug and will function abnormally when they are absent from your system.

Symptoms of Opioid Withdrawal

There are many symptoms of opioid withdrawal. The following are the five more common symptoms:

Flu-like Symptoms

Runny nose, body aches, and diarrhea are all common flu-like symptoms felt during withdrawal from opioids. When the body is deprived of opioids, it causes a chemical imbalance. This imbalance leads to multiple body systems functioning abnormally, including the immune system.

Agitation & Anxiety

This is also thought to occur due to the chemical imbalance in the brain. The lack of opioids leaves the brain wanting more dopamine release and no way to get it. These symptoms are thought to be dependent on how strong a tolerance a person has developed. The higher the dose that was accustomed to, the more extended the fall will be during the withdrawal process. This can cause extreme mood swings, which then trigger the onset of anxiety in someone detoxing from opioids.


Insomnia is thought to occur more due to the pain of withdrawing from the medication than anything else. It is devastating to the body, though, because it can amplify the other symptoms that are present.

Depressive State

These symptoms are also a result of the chemical imbalance in the brain when opioids are removed. The lack of dopamine, compared to the amount the body now considers to be normal, wreaks havoc on the mood center of the pain. It can cause extreme sadness or dissatisfaction in a person experiencing withdrawal.

Excessive Sweating

This often occurs in people withdrawing from opioids. As the body tries to remain in homeostasis with the brain, it is also affected by the chemical change. The body can sweat during all hours of the night, which can contribute to poor sleep too. Other opioid withdrawal symptoms to be aware of include:

  • Restlessness
  • Increased heart rate and blood pressure
  • Goosebumps on the skin
  • Dilated pupils

Opioid Withdrawal Timeline

The average person could experience the above symptoms somewhere between 12 and 30 hours after the last dose of drugs. In most cases, these symptoms are experienced for four to 10 days. However, if withdrawing from an extended-release opioid, symptoms can last up to 21 days or even longer. It is not always true that withdrawal symptoms end there, though. After the acute symptoms disappear, there can be extended withdrawal symptoms or post-acute withdrawal symptoms (PAWS). This recovery can last for months at a time and include symptoms like:

  • Depression and anxiety
  • Insomnia and fatigue
  • Mood swings and diminished decision-making skills

Treatment for Opioid Addiction

Tolerance, dependence, and addiction can all lead to experiencing withdrawal symptoms. Withdrawal is a different experience for each individual and depends significantly on the exact substance and the level of its use. Because this has become such a widespread epidemic, there are currently a wide variety of opioid addiction treatments. These include medication-assisted withdrawal using smaller and smaller doses of extended-release opioid derivatives such as methadone or buprenorphine (Suboxone). Opioid addiction can also include the use of behavioral therapies such as:

  • Cognitive-behavioral therapy – therapy based on the feelings, thoughts, and beliefs about the substance and its effects on the individual.
  • Motivational interviewing – Is used to find what would motivate a person to change and go through recovery.
  • Contingency management – provides tangible rewards for remaining drug-free and recovery-oriented to dissuade further drug use.
  • Family therapy – works to educate family members regarding substance and use issues and improve relationships with the individual in recovery and their family.

Each therapy has its focus, but they all aim to assist the person feel whole again.

Get Help for Opioid Addiction at Vertava Health

If you want to learn more about possible symptoms of opioid withdrawal and treatment for opioid addiction, contact us today at 844.470.0410. One of our specialists is standing by 24/7 to assist you in finding the treatment that is best for you or your loved one.